Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Childhood leukemia and electromagnetic fields: results of a population-based case-control study in Germany
epidem.
[Kinder-Leukämie und elektromagnetische Felder: Ergebnisse einer bevölkerungsbezogenen Fall-Kontroll-Studie in Deutschland]
Von:
Michaelis J, Schüz J, Meinert R, Menger M, Grigat JP, Kaatsch P, Kaletsch U, Miesner A, Stamm A, Brinkmann K, Karner H
Veröffentlicht in: Cancer Causes Control 1997; 8 (2): 167-174
Ziel der Studie (lt. Autor)
Weitere Details
Die Magnetfeld-Exposition wurde mit zwei verschiedenen Methoden der Expositions-Abschätzung ermittelt: Messung über 24 Stunden im Kinderzimmer der Wohnung, in der das Kind vor Diagnosestellung am längsten gewohnt hat, und Kurzzeit-Messungen in allen Wohnungen, in denen das Kind länger als ein Jahr gewohnt hat. Die Exposition wurde in hoch (0,2 µT und mehr) und niedrig (unter 0,2 µT) eingeteilt.
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
- Fragebogen
- Befragung
- Messung: 24-Stunden-Messung im Kinderzimmer und im Wohnzimmer (alle 15 Sekunden); Kurzzeit-Messung innerhalb der Wohnung; Punktmessungen (um Quellen erhöhter Magnetfelder aufzufinden)
- Berechnung: Median während der Nacht (22 - 6 Uhr)
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
Median der 24-Stunden-Messung im Kinderzimmer: < 0,2 µT
|
|
Gruppe 2
|
Median der 24-Stunden-Messung im Kinderzimmer: ≥ 0,2 µT
|
|
Referenzgruppe 3
|
Mittel der 24-Stunden-Messung im Kinderzimmer: < 0,2 µT
|
|
Gruppe 4
|
Mittel der 24-Stunden-Messung im Kinderzimmer: ≥ 0,2 µT
|
|
Referenzgruppe 5
|
Median während der Nacht: < 0,2 µT
|
|
Gruppe 6
|
Median während der Nacht: ≥ 0,2 µT
|
|
Referenzgruppe 7
|
Mittel der Mediane der 24-Stunden-Messungen im Kinder- und Wohnzimmer: < 0,2 µT
|
|
Gruppe 8
|
Mittel der Mediane der 24-Stunden-Messungen im Kinder- und Wohnzimmer: ≥ 0,2 µT
|
|
Referenzgruppe 9
|
Kurzzeit-Messung in der Wohnung, in der das Kind am längsten wohnte: < 0,2 µT
|
|
Gruppe 10
|
Kurzzeit-Messung in der Wohnung, in der das Kind am längsten wohnte: ≥ 0,2 µT
|
|
Referenzgruppe 11
|
Maximum der Kurzzeit-Mess. in allen Wohnungen, in denen das Kind > 1 Jahr wohnte: < 0.2 µT
|
|
Gruppe 12
|
Maximum der Kurzzeit-Mess. in allen Wohnungen, in denen das Kind > 1 Jahr wohnte: ≥ 0.2 µT
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
Juli 1988 - Juni 1993
-
Studienort:
Deutschland (Niedersachsen)
Fallgruppe
Kontrollgruppe
- örtliche und landesweite Kontrolle
-
Auswahl:
-
Matching:
- Geburtsdatum
- Fall:Kontrolle = 1:2
Studiengröße
|
Fälle |
Kontrollen |
| Anzahl geeignet |
219 |
- |
| Anzahl auswertbar |
129 |
328 |
Statistische Analysemethode:
- konditionale logistische Regression
(
Anpassung:
- Geschlecht
- sozioökonomischer Status
- Alter bei Diagnose, Grad der Verstädterung
)
Ergebnisse (lt. Autor)
Einschränkungen (lt. Autor)
Studie gefördert durch
-
Ministry of Health of Lower Saxony, Germany
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-
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-
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-
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-
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(2016):
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-
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(2015):
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-
Salvan A et al.
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-
Pedersen C et al.
(2015):
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-
Tabrizi MM et al.
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-
Pedersen C et al.
(2014):
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-
Ba Hakim AS et al.
(2014):
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-
Swanson J et al.
(2014):
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-
Bunch KJ et al.
(2014):
Residential distance at birth from overhead high-voltage powerlines: childhood cancer risk in Britain 1962-2008
-
Zhao L et al.
(2014):
Magnetic fields exposure and childhood leukemia risk: a meta-analysis based on 11,699 cases and 13,194 controls
-
Sermage-Faure C et al.
(2013):
Childhood leukaemia close to high-voltage power lines--the Geocap study, 2002-2007
-
Schüz J et al.
(2012):
Extremely low-frequency magnetic fields and survival from childhood acute lymphoblastic leukemia: an international follow-up study
-
Jirik V et al.
(2012):
Association between Childhood Leukaemia and Exposure to Power-frequency Magnetic Fields in Middle Europe
-
Swanson J et al.
(2012):
Could the geomagnetic field be an effect modifier for studies of power-frequency magnetic fields and childhood leukaemia?
-
Keegan TJ et al.
(2012):
Case-control study of paternal occupation and childhood leukaemia in Great Britain, 1962-2006
-
Reid A et al.
(2011):
Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to extremely low frequency electromagnetic fields
-
Wünsch Filho V et al.
(2011):
Exposure to magnetic fields and childhood acute lymphocytic leukemia in Sao Paulo, Brazil
-
Kheifets L et al.
(2010):
Pooled analysis of recent studies on magnetic fields and childhood leukaemia
-
Sohrabi MR et al.
(2010):
Living near overhead high voltage transmission power lines as a risk factor for childhood acute lymphoblastic leukemia: a case-control study
-
Kroll ME et al.
(2010):
Childhood cancer and magnetic fields from high-voltage power lines in England and Wales: a case-control study
-
Malagoli C et al.
(2010):
Risk of hematological malignancies associated with magnetic fields exposure from power lines: a case-control study in two municipalities of northern Italy
-
Hug K et al.
(2010):
Parental occupational exposure to extremely low frequency magnetic fields and childhood cancer: a German case-control study
-
Rahman HIA et al.
(2008):
A case-control study on the association between environmental factors and the occurrence of acute leukemia among children in Klang Valley, Malaysia
-
Bernard N et al.
(2008):
Assessing the potential leukemogenic effects of 50 Hz magnetic fields and their harmonics using an animal leukemia model
-
Schüz J et al.
(2007):
Nighttime exposure to electromagnetic fields and childhood leukemia: an extended pooled analysis
-
Svendsen AL et al.
(2007):
Exposure to magnetic fields and survival after diagnosis of childhood leukemia: a German cohort study
-
Kabuto M et al.
(2006):
Childhood leukemia and magnetic fields in Japan: a case-control study of childhood leukemia and residential power-frequency magnetic fields in Japan
-
Foliart DE et al.
(2006):
Magnetic field exposure and long-term survival among children with leukaemia
-
Draper G et al.
(2005):
Childhood cancer in relation to distance from high voltage power lines in England and Wales: a case-control study
-
Schüz J et al.
(2001):
Residential magnetic fields as a risk factor for childhood acute leukaemia: results from a German population-based case-control study
-
Greenland S et al.
(2000):
A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Childhood Leukemia-EMF Study Group
-
UK Childhood Cancer Study Investigators
(2000):
Childhood cancer and residential proximity to power lines
-
Ahlbom A et al.
(2000):
A pooled analysis of magnetic fields and childhood leukaemia
-
McBride ML et al.
(1999):
Power-frequency electric and magnetic fields and risk of childhood leukemia in Canada
-
Angelillo IF et al.
(1999):
Residential exposure to electromagnetic fields and childhood leukaemia: a meta-analysis
-
Dockerty JD et al.
(1998):
Electromagnetic field exposures and childhood cancers in New Zealand
-
Michaelis J et al.
(1998):
Combined risk estimates for two German population-based case-control studies on residential magnetic fields and childhood acute leukemia
-
Tynes T et al.
(1997):
Electromagnetic Fields and Cancer in Children Residing Near Norwegian High-Voltage Power Lines
-
Petridou E et al.
(1997):
Electrical power lines and childhood leukemia: a study from Greece
-
Preston-Martin S et al.
(1996):
Los Angeles study of residential magnetic fields and childhood brain tumors
-
Olsen J et al.
(1993):
Residence near high voltage facilities and risk of cancer in children
-
Feychting M et al.
(1993):
Magnetic fields and cancer in children residing near Swedish high-voltage power lines
-
Verkasalo PK et al.
(1993):
Risk of cancer in Finnish children living close to power lines
-
Petridou E et al.
(1993):
Age of exposure to infections and risk of childhood leukaemia
-
London SJ et al.
(1991):
Exposure to residential electric and magnetic fields and risk of childhood leukemia
-
Coleman MP et al.
(1989):
Leukaemia and residence near electricity transmission equipment: a case-control study
-
Savitz DA et al.
(1988):
Case-control study of childhood cancer and exposure to 60-Hz magnetic fields
-
Tomenius L
(1986):
50-Hz electromagnetic environment and the incidence of childhood tumors in Stockholm County
-
Wertheimer N et al.
(1979):
Electrical wiring configurations and childhood cancer
