Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Occupational exposure to magnetic fields and the risk of brain tumors
epidem.
[Berufliche Exposition bei Magnetfeldern und das Risiko für Hirntumor]
Von:
Coble JB, Dosemeci M, Stewart PA, Blair A, Bowman J, Fine HA, Shapiro WR, Selker RG, Loeffler JS, Black PM, Linet MS, Inskip PD
Veröffentlicht in: Neuro Oncol 2009; 11 (3): 242-249
Ziel der Studie (lt. Autor)
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
- Fragebogen: Berufstätigkeit mit Berufsbezeichnung, Industriezweig, Beginn und Ende, Art der Beschäftigung (z.B. Vollzeit, Teilzeit, Saison) für alle jemals mindestens sechs Monate lang ausgeübten Tätigkeiten; detaillierte Fragen zu Berufsbezeichnungen mit möglicher Exposition bei Magnetfeldern (Tätigkeit, Art und Größe der benutzten elektrisch angetriebenen Werkzeuge oder Geräte, mittlerer Abstand zum Gerät; Zeitdauer, die bei der Arbeit mit oder in der Nähe von elektrisch angetriebenen Geräten verbracht wurde)
- Job-Exposure-Matrix: Anpassung der Expositions-Schätzer basierend auf den berufsspezifischen Fragebögen
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
maximal exponierter Beruf: ≤ 0,15 µT
|
|
Gruppe 2
|
maximal exponierter Beruf: > 0,15 - 0,3 µT
|
|
Gruppe 3
|
maximal exponierter Beruf: ≥ 0,3 µT
|
|
Referenzgruppe 4
|
Dauer über 0,15 µT: 0 Jahre
|
|
Gruppe 5
|
Dauer über 0,15 µT: > 0 - 15 Jahre
|
|
Gruppe 6
|
Dauer über 0,15 µT: > 15 Jahre
|
|
Referenzgruppe 7
|
durchschnittliche Exposition: ≤ 0,15 µT
|
|
Gruppe 8
|
durchschnittliche Exposition: > 0,15 - 0,3 µT
|
|
Gruppe 9
|
durchschnittliche Exposition: ≥ 0,3 µT
|
|
Referenzgruppe 10
|
Gesamt-Exposition über 0,15 µT: 0
|
|
Gruppe 11
|
Gesamt-Exposition über 0,15 µT: > 0 - 0.45 µT-Jahre
|
|
Gruppe 12
|
Gesamt-Exposition über 0,15 µT: > 0.45 µT-Jahre
|
Population
-
Gruppe:
-
Beobachtungszeitraum:
1994 - 1998
-
Studienort:
USA (Phoenix, Arizona; Boston, Massachusetts, and Pittsburgh, Pennsylvania)
Fallgruppe
-
Merkmale:
Patienten mit Gliom oder Meningiom
-
Datenquelle:
3 auf die Behandlung von Hirntumor spezialisierte Krankenhäuser
Kontrollgruppe
-
Auswahl:
-
Matching:
- Geschlecht
- Alter
- Region
- Ethnie
- Entfernung zwischen Wohnung und Krankenhaus
Studiengröße
|
Fälle |
Kontrollen |
| Anzahl geeignet |
686 |
799 |
Statistische Analysemethode:
- unkonditionale logistische Regression
(
Anpassung:
- Alter
- Geschlecht
- Krankenhaus
)
Ergebnisse (lt. Autor)
Studie gefördert durch
-
National Cancer Institute (NCI; U.S. National Institutes of Health), Maryland, USA
Themenverwandte Artikel
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Carlberg M et al.
(2020):
Case-control study on occupational exposure to extremely low-frequency electromagnetic fields and the association with acoustic neuroma
-
Carlberg M et al.
(2018):
Case-Control Study on Occupational Exposure to Extremely Low-Frequency Electromagnetic Fields and the Association with Meningioma
-
Carlberg M et al.
(2017):
Case-control study on occupational exposure to extremely low-frequency electromagnetic fields and glioma risk
-
Zhang Y et al.
(2016):
Meta-analysis of extremely low frequency electromagnetic fields and cancer risk: a pooled analysis of epidemiologic studies
-
Turner MC et al.
(2014):
Occupational exposure to extremely low frequency magnetic fields and brain tumour risks in the INTEROCC study
-
Sorahan T
(2014):
Magnetic fields and brain tumour risks in UK electricity supply workers
-
Marcilio I et al.
(2011):
Adult mortality from leukemia, brain cancer, amyotrophic lateral sclerosis and magnetic fields from power lines: a case-control study in Brazil
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(2011):
Occupational and residential exposure to electromagnetic fields and risk of brain tumors in adults: a case-control study in Gironde, France
-
Kheifets L et al.
(2008):
Occupational electromagnetic fields and leukemia and brain cancer: an update to two meta-analyses
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(2007):
Occupational exposure to ionizing and non-ionizing radiation and risk of glioma
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Karipidis KK et al.
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Occupational exposure to low frequency magnetic fields and the risk of low grade and high grade glioma
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Risk for leukaemia and brain and breast cancer among Danish utility workers: a second follow-up
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-
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