• experimental
  
• epidemiological
  

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Medical/biological Study (experimental study)

GSM base station electromagnetic radiation and oxidative stress in rats. med./biol.

PubMed Entry

Journal web site

Aim of study (according to author)
To study the effects of GSM base transceiver station electromagnetic irradiation on oxidative stress and generation of free radicals in rats.
Background/further details:
9 rats were exposed, 9 rats were sham-exposed.

Endpoint

• oxidative stress

Exposure
General category: digital mobile phone, cell phone base station, GSM

Field characteristics	Parameters
945 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, for 8 days	electric field strength: 37.2 V/m peak value power flux density: 3.67 W/m² peak value SAR: 11.3 mW/kg mean value (whole body)

Exposed system:
animal (species/strain): rat/Wistar albino
whole body exposure

Methods
Endpoint/Measurement parameters/Methodology

• molecular biosynthesis: level of malondialdehyde (as lipid peroxidation marker) and glutathione (spectrophotometry)
• others: oxidative stress (malondialdehyde production, glutathione level (see "molecular biosynthesis"), enzyme activity of superoxide dismutase (for antioxidant status evaluation); spectrophotometry); body weight; food and water consumption

Main outcome of study (according to author)
When electromagnetic fields at a power density of 3.67 W/m² were applied malondialdehyde level increased and glutathione concentration decreased significantly. Additionally, there was a less significant increase in superoxide dismutase activity under exposure.
The data indicate that exposure to electromagnetic fields at base station frequency may modulate the oxidative stress in rats.

(Study character: medical/biological study, experimental study, full/main study)

Study funded by

• Bogazici University Research Fund, Turkey
• Istanbul University Research Fund, Turkey

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