Study type: Medical/biological study (experimental study)

Effect of low power microwave on the mouse genome: a direct DNA analysis med./bio.

By: Sarkar S, Ali S, Behari J
Published in: Mutation Research - Genetic Toxicology 1994; 320 (1-2): 141-147
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Aim of study (acc. to author)

To evaluate the potential mutagenic effect of microwave in mice exposed at 1 mW/cm² by direct DNA analysis.

Background/further details

HinfI (a restriction enzyme) digested DNA samples from testis and brain were hybridized with a synthetic oligo probe.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 2 h/day for 120, 150 and 200 days.

General information

A total of six exposed and four control animals were used in this study.

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Exposure duration 2 h/day for 120, 150 and 200 days.
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 2 m
Setup mice were placed into a 0.5 cm thick acrylic cage which was placed symmetrically along the midline of the antenna aperture.
Parameters
Measurand Value Type Method Mass Remarks
power density 10 W/m² mean measured - -
SAR 1.18 mW/g unspecified calculated - -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Band profiles in exposed animals were found to be distinctly altered in the range of 7-8 kb which was also substantiated by densitometric analysis.

Study character:

Study funded by

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