Medical/biological Study (observational study)
Is newborn melatonin production influenced by magnetic fields produced by incubators? med./biol. By: Bellieni CV, Tei M, Iacoponi F, Tataranno ML, Negro S, Proietti F, Longini M, Perrone S, Buonocore G
Published in: Early Hum Dev 2012; 88 (8): 707 - 710 ( PubMed Entry , Journal web site )
Aim of study (according to author)
To assess melatonin production in a group of newborns exposed to electromagnetic fields within incubators.
The study group consisted of 28 babies who had spent at least 48 h in incubators. 6-hydroxymelatoninsulfate (6-OHMS) urine excretion (normalized to creatinine) was measured at the end of their stay in the incubators and 48 h later when they have been in cribs where electromagnetic fields were below the detectable limit.
The control group consisted of 27 babies who were not exposed to electromagnetic fields. Two urine samples were collected (taken 48 h apart from each other).
- endocrine changes: melatonin production
General category: magnetic field, 50/60 Hz (AC), LF therapeutical/medical device
FIELD View further expo parameters
whole body exposure
Methodsinvestigated material: urine samples
investigated organ system: endocrine system
time of investigation: after exposure
Main outcome of study (according to author)
Mean 6-hydroxymelatoninsulfate values were increased 48 h after the exposed babies were removed from the incubators and put into the cribs. In the control group, mean 6-hydroxymelatoninsulfate values were not significantly different in the first and in the second sample and similar to the first value of the exposed babies in the incubator.
The authors conclude that the transient increase in melatonin production after removing newborns from incubators demonstrates a possible influence of electromagnetic fields on melatonin production in newborns.
(Study character: medical/biological study, observational study, full/main study)
Study funded byRelated articles
Glossary: 6-hydroxymelatoninsulfate, 50/60 Hz, AC, biological, control group, creatinine, electromagnetic fields, ELISA, endocrine, endocrine system, endpoint, excretion, exposed, exposure, full/main study, human, incubator, LF, magnetic field, magnetic flux density, mean, melatonin, power, significantly, transient, urine, whole body exposure
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- Crasson M et al. (2001): Daytime 50 Hz magnetic field exposure and plasma melatonin and urinary...
- Wood AW et al. (1998): Changes in human plasma melatonin profiles in response to 50 Hz magnetic field...
- Bullough J et al. (1996): Light and magnetic fields in a neonatal intensive care unit.
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