Medical/biological Study (experimental study)
Resonance effect of microwaves on the genome conformational state of E. coli cells. med./biol. By: Belyaev IY, Alipov YD, Shcheglov VS, Lystsov VN
Published in: Z Naturforsch [C] 1992; 47 (7-8): 621 - 627 ( PubMed Entry , Journal web site )
Aim of study (according to author)
The influence of millimeter waves on the process of the genome conformational state (GCS) repair after E. coli cell exposure to X-rays was examined.
As a test for appearance and repair of changes in a chromosomal DNA the method of the anomalous viscosity time dependencies (AVTD) in cell lysates was used.
General category: low level microwaves
FIELD View further expo parameters
bacterium (in vitro)
Escherichia coli/K12 (different strains)
Methodsinvestigated material: cell lysates
time of investigation: after exposure
Main outcome of study (according to author)
Radiation of E. coli cells with doses of 10-50 Gy led to changes of the AVTD curve of the cell lysate. After post-irradiated cell incubation of 90-120 min (depending on the dose of radiation), an almost complete recovery of the AVTD curve took place. This means that during this period the genome conformational state of the exposed cells returned to the control level ("repair" of genome conformational state).
The "repair" of genome conformational state of bacterial cells after ionizing irradiation is highly sensitive to the resonance effect of millimeter waves (microwaves suppress the "repair"): Within the ranges of 51.62-51.84 GHz and 41.25-41.50 GHz the frequency dependence of the observed effect has a resonance nature. The power dependence of the microwave effect within the range of 0.1-200 µW/cm² has shown that a power density of 1 µW/cm² is sufficient to suppress radiation-induced repair of the genome conformational state. The effect of microwave suppression of repair does not depend on the sequence of cell exposure to X-rays and microwave radiation.
The data indicate the role of the cell genome in the resonant interaction of cells with low intensity millimeter waves.
(Study character: medical/biological study, experimental study, full/main study)
Study funded byRelated articles
Glossary: acoustic, AVTD, bacterial, biological, calorimetric, cell, chromosomal, conformational, DNA, dose, E. coli, endpoint, exposed, exposure, frequency, full/main study, genome, genotoxicity, GHz, Gy, incubation, induced, in vitro, ionizing, irradiated, lysate, microwave, Millimeter waves, mutation, power, power density, radiation, resonant, SAR, strains, viscosity, X-rays
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