Aim of study (according to author)
The objective of this study was to investigate whether the exposure of a radiofrequency field of 900 MHz may induce the expression of the p53 protein and its activation by phosphorylation in cultured human amniotic cells.
Four average specific absorption rates were used to examine, if there is a change in the expression level of p53 protein and its phosphorylation of the serine residues 15 and 37. In response to a genetic damage, this protein is activated and can induce cell cycle arrest allowing more time for DNA repair or elimination of damaged cells through apoptosis. Cells were treated with Bleomycin as a positive control.
General category: mobile communication system, mobile phone, GSM, PW (pulsed wave)
| 900 MHz|
exposure duration: continuous for 24 h
|SAR: 4 W/kg average over time (0.25, 1, 2, 4 W/kg)|
SAR: 32 W/kg peak value (2, 8, 16, 32 W/kg)
intact cell/cell culture (in vitro)
Main outcome of study (according to author)
The data indicated no significant changes in the expression and activation of the p53 protein between exposed and sham-exposed cells. The authors suggest that a radiofrequency field exposure at 900 MHz does not induce the p53 pathway and cellular stress.
(Study character: medical/biological study, experimental study, full/main study)
Study funded by
© 1997 - 2013, Research Center for Bioelectromagnetic Interaction (femu - RWTH Aachen University, Germany).
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