EMF-Portal - Experimental studies of brain tumour development during exposure to continuous and pulsed 915 MHz radiofrequency radiation (1993)

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Experimental studies of brain tumour development during exposure to continuous and pulsed 915 MHz radiofrequency radiation. med./biol.

By: Salford LG, Brun A, Persson BR, Eberhardt J
Published in: Bioelectrochem Bioenerg 1993; 30 : 313 - 318 ( open external web page

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Aim of study (according to editor)
To investigate the effects of electromagnetic field exposure in a rat brain glioma model.

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Endpoint

cancer: brain tumor

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Exposure
General category: mobile communication system, GSM, microwaves

Field characteristics	Parameters
field 1: 915 MHz continuous wave (CW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10-15 days	power: 1 W peak value SAR: 1.67 W/kg
field 2: 915 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10 days	power: 2 W peak value SAR: 0.0077 W/kg
field 3: 915 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 10 days	power: 2 W peak value SAR: 0.016 W/kg
field 4: 915 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 13 days	power: 2 W peak value SAR: 0.03 W/kg
field 5: 915 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 9 days	power: 2 W peak value SAR: 0.4 W/kg
field 6: 915 MHz pulsed (PW) exposure duration: repeated daily exposure, 7 h/day, 5 days/week, for 9-13 days	power: 2 W peak value SAR: 1 W/kg

FIELD View further expo parameters

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Exposed system:
animal (species/strain): rat/Fischer 344

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Methods
Endpoint/Measurement parameters/Methodology

cancer: brain tumor (size of tumour area) induced by injected rat glioma RG2 cells
thermoregulation: rectal temperature

investigated material: tissue slices (in vitro), isolated organ (in vitro)
investigation on living organism
investigated organ system: brain/CNS

time of investigation: during and after exposure

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Main outcome of study (according to author)
The results does not show a significant difference in tumor size between animals exposed to 915 MHz microwaves, and those not exposed. The rectal temperature recorded before, at 4h and directly after exposure did not fall or rise.

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(Study character: medical/biological study, experimental study, full/main study)

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Study funded by

Ake Wibergs Foundation, Sweden
Crafoord Foundation, Sweden
Gunnar, Arvid and Elisabeth Nilssons Research Foundation, Sweden
University of Lund, Sweden

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Glossary: animals, biological, brain, brain tumor, cancer, cells, CNS, CW, electromagnetic field, endpoint, exposed, exposure, Fischer 344, full/main study, glioma, GSM, induced, injected, in vitro, MHz, microwaves, mobile communication, organ, organism, power, pulsed, PW, rat, rectal temperature, SAR, significant, species, strain, thermoregulation, tissue, tumor

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