Medical/biological Study (experimental study)
Effect of Exposure to Static, High Voltage Electric Field Generated Nearby HVDC Transmission Lines on Antioxidant Activity of Hepatocytes in Rats. med./biol. By: Cieslar GJ, Fiolka J, Mrowiec J, Sowa P, Kasperczyk S, Birkner E, Sieron A
Published in: The Electromagnetics Academy (2009): "PIERS Proceedings, Moscow, Russia", The Electromagnetics Academy (ISBN 978-1-934142-10-3, 2021 pages): 1092 - 1096 ( full article )
Aim of study (according to author)
To study the effect of long-term exposure to strong, static electric field generated by high voltage direct current transmission lines on activity of some antioxidant enzymes in liver homogenates of rats.
64 (96?; contradictory statements in the abstract and methods) male rats were divided into one/two exposure group(s) (contradictory statements) and a sham exposure group (each group n=32). At 14, 28, 56 days of exposure as well as at 28 days after exposure termination, 8 rats were killed and investigated.
General category: static electric field, DC, power transmission line, high-voltage direct current (HVDC)
exposure duration: continuous for 8 h/day for up to 56 days
|electric field strength: 25 kV/m |
FIELD View further expo parameters
animal (species/strain): rat/Wistar
whole body exposure
Methodsinvestigated material: liver homogenates
time of investigation: during and after exposure
Main outcome of study (according to author)
Enzyme activities of glutathione peroxidase and glutathione reductase were significantly increased in the electric field-exposed group at the 56th day of exposure and enzyme activity of superoxide dismutase significantly decreased at the 14th day of exposure. No statistically significant changes were found in the enzyme activities of catalase and glutathione S-transferase both during and after the end of exposure.
Additionally, in exposed rats a significant decrease in malondialdehyde concentration in liver homogenates at 28 days after the end of exposure was found as compared to the control group.
The authors conclude, that strong static electric fields with characteristics of those generated by high voltage direct current transmission lines do not cause any persistent unfavorable effects on antioxidant reactions in the liver of rodents.
(Study character: medical/biological study, experimental study, full/main study)Related articles
Glossary: animal, antioxidant, biological, catalase, control group, DC, electric field, electric field strength, endpoint, enzyme activity, enzymes, exposed, exposure, full/main study, glutathione peroxidase, glutathione reductase, glutathione S-transferase, High Voltage Direct Current transmission lines, homogenates, liver, malondialdehyde, oxidative stress, power transmission line, rat/Wistar, rats, sham exposure, significant, species, spectrophotometry, static electric fields, statistically, strain, superoxide dismutase, whole body exposure
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