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Medical/biological Study (experimental study)Single strand DNA breaks in rat brain cells exposed to microwave radiation. med./biol. By: Paulraj R, Behari J
Published in: Mutat Res 2006; 596 (1-2): 76 - 80 (  PubMed Entry , Journal web site )Aim of study (according to author)
To investigate the effect of microwave exposure (2.45 and 16.5 GHz) on developing rat brain (35 days old).
Background/further details:
Six rats per exposure and sham exposure condition were used (n=24). Endpoint Exposure
General category: radio frequency field, 2.45 GHz | Field characteristics | Parameters |
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field 1: 2.45 GHz 
exposure duration: continuous for 2 hr/day on 35 days | SAR: 1 W/kg
power flux density: 0.344 mW/cm²
| field 2: 16.5 GHz
exposure duration: continuous for 2 hr/day on 35 days | SAR: 2.01 W/kg
power flux density: 1 mW/cm²
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FIELD View further expo parametersExposed system:
animal (species/strain): rat/Wistar
whole body exposure Methods
Endpoint/Measurement parameters/Methodology investigated material: DNA/RNA (in vitro), cell lysates
investigated organ system: brain/CNS
time of investigation: after exposure
Main outcome of study (according to author)
The data showed that the chronic exposure to 2.45 and 16.5 GHz under these experimental conditions caused a statistically significant increase in DNA single-strand breaks (increase in the length of DNA migration) in brain cells of rats. (Study character: medical/biological study, experimental study, full/main study)
Study funded by - Indian Council of Medical Research (ICMR), India
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Glossary: animal, biological, brain, cells, chronic exposure, CNS, comet assay, DNA, endpoint, exposure, full/main study, genotoxicity, GHz, in vitro, lysates, microwave, migration, mutation, power flux density, radio frequency, rat/Wistar, rats, RNA, SAR, sham exposure, significant, single-strand breaks, species, statistically, strain, whole body exposure |
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