|
|
|
 |
Medical/biological Study (experimental study)Sex-specific differences in changes of disturbed functional activity of platelets in albino rats under the effect of terahertz electromagnetic radiation at nitric oxide frequencies. med./biol. By: Kirichuck VF, Ivanov AN, Antipova ON, Krenickiy AP, Mayborodin AV, Tupikin VD
Published in: Bull Exp Biol Med 2008; 145 (1): 75 - 77 (  PubMed Entry , Journal web site )Aim of study (according to author)
To examine the characteristic features of platelet reaction to microwave exposure (150.176 - 150.664 GHz) in rats exposed to acute immobilization stress.
Background/further details:
Microwaves of the frequencies 150.176 to 150.664 GHz correspond to frequencies of the molecular radiation and absorption spectrum of nitric oxide. One of the features of nitric oxide is the inhibition of platelet aggregation which occurs as a reaction to stress.
In this study, immobilization stress was induced by fixation of the animals in the supine posture for 3 hours. 60 male rats, 60 female estrus rats, and 60 female diestrus rats were investigated. The animals were divided into following groups: 1) control, 2) stressed animals, 3) stressed animals exposed to microwaves for 15 min, and 4) stressed animals exposed to microwaves for 30 min. Endpoint - cell function: functional activity of platelets as stress response
Exposure
General category: microwaves | Field characteristics | Parameters |
|---|
150.176  - 150.664 GHz
exposure duration: continuous for 15 min. or 30 min. |
|
FIELD View further expo parametersExposed system:
animal (species/strain): rat/albino
whole body exposure Methods
Endpoint/Measurement parameters/Methodology - cell function: functional activity of platelets (platelet aggregations (laser analyzer))
investigated material: intact cell/cell culture (in vitro), blood sample
investigation on living organism
time of investigation: after exposure
Main outcome of study (according to author)
Functional activity in platelets was increased in rats of both sexes in a state of acute immobilization stress. Exposure of stressed animals to microwaves in the nitric oxide frequency band restored the impaired platelet aggregation activity. Female rats were more sensitive and gained complete recovery of platelet aggregation after 15 min exposure whereas in male rats complete recovery was observed only after 30 min exposure. 30 min exposure led in stressed diestrus rats to complete recovery whereas a reduced functional activity of platelets was observed in stressed estrus rats.
The authors concluded that female rats were more sensitive to the microwave exposure than male rats. Furthermore, a relationship between exposure and phase of estrous cycle was found: estrus female rats exhibited maximum sensitivity to microwave exposure. (Study character: medical/biological study, experimental study, full/main study)
Glossary: absorption spectrum, acute, aggregation, animals, biological, blood, cell, cell culture, endpoint, estrous cycle, estrus, exposed, exposure, frequencies, frequency band, full/main study, GHz, immobilization, induced, inhibition, in vitro, laser, microwave, molecular, nitric oxide, platelet, radiation, rats, sensitivity, species, strain, stress, supine, whole body exposure |
|
|
© 1997 - 2010, Research Center for Bioelectromagnetic Interaction (femu - RWTH Aachen University, Germany). The informational contents of the EMF-Portal are available free of charge for personal and strictly non-commercial purposes. The informational contents of the EMF-Portal may be retrieved, read or printed, but not (i) copied, (ii) changed or (iii) saved in any format, neither electronically nor on other storage media. Permissions for publication, reproduction, commercial purposes or third party propagation of contents of the EMF-Portal – including partial excerpts or revised formats – have to be obtained from the femu Aachen University-copyright holders. By retrieving, reading or printing these documents you expressly state your agreement with all conditions in the fine print. |
|
Sign Up
