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Medical/biological Study (experimental study)Behavioral effect of terahertz waves in male mice. med./biol. By: Bondar NP, Kovalenko IL, Avgustinovich DF, Khamoyan AG, Kudryavtseva NN Published in: Bull Exp Biol Med 2008; 145 (4): 401 - 405 ( PubMed Entry , Journal web site )Aim of study (according to author) To study the effect of terahertz waves (3.6 THz) on the behavior of mice. Background/further details: In the first series of experiments, explorative behavior during exposure was investigated in following groups: an exposure group, a control group and a sham exposure group (exposed to a 30-40 mW electricity supply device). In the second series, anxiety behavior was investigated one day after exposure (30 min) in an elevated plus-maze (exposed group and control group). Each group consisted of 10-12 male mice. Endpoint Exposure General category: terahertz fields | Field characteristics | Parameters |
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field 1: 3.6 THz  exposure duration: continuous for 15 min. | power: 15 mW
| field 2: 3.6 THz  exposure duration: continuous for 30 min. | power: 15 mW
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FIELD View further expo parametersExposed system: animal (species/strain): mouse/C57BL/6J whole body exposure Methods Endpoint/Measurement parameters/Methodology - cognitive/behavioural endpoints: explorative behavior (number and total time of sniffing the cage hole through which the THz laser passes, number and total time of approaches to the barrier and of tearing/strewing the bedding; time spent near the hole, and in the area of THz laser); anxiety (behavior in elevated plus maze)
investigation on living organism
time of investigation: during and after exposure
Main outcome of study (according to author) In the first series of experiments, the exposed animals showed a decreased explorative activity compared to the control group. In the second series, the number of entries into the central area was lower and the number of entries in the closed arms was higher in the exposed group, no entry into the open arms was observed. The authors concluded that mice perceived terahertz waves even during short-term exposure and showed increased anxiety on the day after 30-min exposure. (Study character: medical/biological study, experimental study, full/main study)
Study funded by Glossary: animals, anxiety, behavior, biological, cognitive, control group, electricity, elevated plus maze, endpoint, exposed, exposure, full/main study, laser, power, sham exposure, species, strain, Terahertz waves, whole body exposure |
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