Medical/biological Study (experimental study)
Magnetosensory function in rats: localization using positron emission tomography. med./biol.
By: Frilot 2nd C, Carrubba S, Marino AA
Published in: Synapse 2009; 63 (5): 421 - 428 (PubMed
| Journal website
Aim of study (according to author)
To show that electromagnetic fields produce magnetosensory evoked potentials in rats and to localize the activated region in the brain.
The authors wanted to extend results from previous studies on magnetosensory evoked potentials in humans (publication 15027) and rabbits (publication 9242).
In the first experiment, 10 female rats were exposed to a magnetic field. In a second experiment, the effect of the magnetic field on the regional rate of glucose uptake was analyzed in another group of 10 rats using PET. Each rat was scanned twice: after field exposure and after sham exposure.
- effects on the neurological system: magnetosensory evoked potentials; neuroanatomical localization
Exposure FIELD View further expo parameters
General category: magnetic field, low frequency field, 50/60 Hz (AC)
animal (species/strain): rat/Sprague-Dawley
whole body exposure
- effects on the neurological system: onset- and offset- magnetosensory evoked potentials (EEG); neuroanatomical localization (fluorodeoxyglucose uptake: PET)
investigation on living organism
investigated organ system: brain
time of investigation: during exposure
Main outcome of study (according to author)
Onset magnetosensory evoked potentials were detected in all 10 rats, and offset magnetosensory evoked potentials were detected in 7 of the 10 rats.The magnetosensory evoked potentials were similar in magnitude, latency and dynamical origin to those exhibited by rabbits (see publication 9242) and humans (see publication 15027). Exposure to the magnetic field stimulated cerebellar uptake of fluorodeoxyglucose compared to the sham exposure in the same animals. The activated region was located in the posterior central cerebellum.
The results indicated that magnetosensory evoked potentials in rats were associated with increased glucose utilization in the cerebellum, thereby supporting earlier evidence that electromagnetic field transduction occurred in the brain.
(Study character: medical/biological study, experimental study, full/main study)
Study funded by
- Frilot 2nd C et al. (2011): Transient and steady-state magnetic fields induce increased fluorodeoxyglucose...
- Volkow ND et al. (2011): Effects of cell phone radiofrequency signal exposure on brain glucose...
- Carrubba S et al. (2009): The electric field is a sufficient physical determinant of the human magnetic...
- Carrubba S et al. (2008): The effects of low-frequency environmental-strength electromagnetic fields on...
- Carrubba S et al. (2008): Magnetosensory evoked potentials: consistent nonlinear phenomena.
- Carrubba S et al. (2007): Evidence of a nonlinear human magnetic sense.
- Cvetkovic D et al. (2006): Alterations in Human EEG Activity Caused by Extremely Low Frequency...
- Carrubba S et al. (2006): Detection of nonlinear event-related potentials.
- Ghione S et al. (2005): Effects of 50 Hz electromagnetic fields on electroencephalographic alpha...
- Marino AA et al. (2003): Localization of electroreceptive function in rabbits.
- Marino AA et al. (2003): Consistent magnetic-field induced dynamical changes in rabbit brain activity...
- Marino AA et al. (2002): Consistent magnetic-field induced dynamical changes in rabbit brain activity...
- Sonnier H et al. (2001): Sensory transduction as a proposed model for biological detection of...
- Bell GB et al. (1992): Alterations in brain electrical activity caused by magnetic fields: detecting...
Glossary: 50/60 Hz
, electromagnetic field
, evoked potentials
, full/main study
, low frequency field
, magnetic field
, magnetic flux density
, sham exposure
, whole body exposureExposure: magnetic field
, low frequency field
, 50/60 Hz