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Medical/biological Study (experimental study)

Microwave-induced chronotropic effects in the isolated rat heart. med./biol.

By: Olsen RG, Lords JL, Durney CH
Published in: Ann Biomed Eng 1977; 5 (4): 395 - 409 ( open external web page PubMed Entry , open external web page Journal web site )

Aim of study (according to author)
To investigate the effects of microwave exposure on the heart rate of isolated and perfused rat hearts in combination with use of atropine or propranolol. Atropine acts blocking at the parasympathetic nervous system, whereas propranolol acts blocking at the sympathetic nervous system.

Endpoint

Exposure
General category: radio frequency field, microwaves, CW (continuous wave)

Field characteristicsParameters
field 1: 960 MHz
continuous wave (CW)
SAR: 1.3 mW/g
field 2: 960 MHz
continuous wave (CW)
SAR: 2.1 mW/g

FIELD View further expo parameters

Exposed system:
isolated organ (in vitro)
isolated rat heart

Methods
Endpoint/Measurement parameters/Methodology

investigated material: isolated organ (in vitro)
investigated organ system: cardiovascular system

time of investigation: during exposure

Main outcome of study (according to author)
Microwave exposure induced bradycardia in isolated and perfused rat hearts. Hearts treated with atropin showed strong tachycardia during irradiation, even more stronger than atropin alone. On the other hand, hearts treated with propranolol showed stronger bradycardia during exposure than seen with propranolol alone.

(Study character: medical/biological study, experimental study, full/main study)

Study funded by

  • not stated/none

Glossary: atropine, biological, bradycardia, cardiovascular system, CW, endpoint, exposure, full/main study, heart rate, hearts, induced, in vitro, irradiation, microwave, organ, parasympathetic nervous system, propranolol, radio frequency field, rat, SAR, strain, sympathetic nervous system, tachycardia

© 1997 - 2013, Research Center for Bioelectromagnetic Interaction (femu - RWTH Aachen University, Germany).

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