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Medical/biological Study (experimental study)

Biological and morphological effects on the brain after exposure of rats to a 1439 MHz TDMA field. med./biol.

By: Tsurita G, Nagawa H, Ueno S, Watanabe S, Taki M
Published in: Bioelectromagnetics 2000; 21 (5): 364 - 371 ( open external web page PubMed Entry , open external web page Journal web site )

Aim of study (according to author)
To investigate the athermal effects of exposure to a 1439 MHz TDMA field, as used in cellular phones, on the permeability of the blood-brain barrier, on the morphological changes of the brain and on body-mass fluctuations.

Endpoint

Exposure
General category: mobile communication system, digital mobile phone, PDC, TDMA

Field characteristicsParameters
field 1: 1.439 GHz
pulsed (PW)
exposure duration: repeated daily exposure for 1 h/day for 5 consecutive days and 2 days of rest, for 2 or 4 weeks
SAR: 2 W/kg peak value (brain)
SAR: 0.25 W/kg mean value (whole body)
field 2: RF
exposure duration: continuous for 2 h
SAR: 20 W/kg average over mass (brain)

FIELD View further expo parameters

Exposed system:
animal (species/strain): rat/Sprague-Dawley
partial body exposure: head

Methods
Endpoint/Measurement parameters/Methodology

investigated material: tissue slices (in vitro)
investigation on living organism
investigated organ system: brain/CNS

time of investigation: during and after exposure

Main outcome of study (according to author)
A 1439 MHz TDMA field did not induce observable changes in the permeability of the blood-brain barrier, morphological changes in the cerebellum, or body mass changes .

(Study character: medical/biological study, experimental study, full/main study)

Study funded by

  • Ministry of Education, Culture, and Science, Japan
  • Ministry of Posts and Telecommunications, Japan

Published comment on this article:Related articles i
Glossary: albumin, animal, athermal effects, biological, blood-brain barrier, brain, cellular phones, cerebellum, CNS, digital, endpoint, evans blue, exposure, full/main study, immunostaining, injection, in vitro, mean value, MHz, mobile communication, morphological, neurological, organism, partial body exposure, PDC, permeability, pulsed, PW, rat/Sprague-Dawley, SAR, serum, species, strain, TDMA, tissue

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