Medical/biological Study (experimental study)
The effect of pulsed 900-MHz GSM mobile phone radiation on the acrosome reaction, head morphometry and zona binding of human spermatozoa. med./biol.
By: Falzone N, Huyser C, Becker P, Leszczynski D, Franken DR
Published in: Int J Androl 2011; 34 (1): 20 - 26 (PubMed
| Journal website
Aim of study (according to author)
The objective of the study was twofold: 1) to investigate the effect of radiofrequency electromagnetic field exposure on sperm head morphometry and the acrosome response and 2) to evaluate the consequence of exposure on the spermatozoa's zona pellucida-binding capacity.
Semen samples were collected from 12 healthy donors. Spermatozoa were investigated immediately, 2 h and 24 h after exposure.
General category: mobile communication system, digital mobile phone, GSM, PW (pulsed wave)
FIELD View further expo parameters
| 900 MHz |
exposure duration: continuous for 1 h
|SAR: 2 W/kg |
- sperm morphology (computerized morphometric assessment of minor and major axes, area, perimeter, acrosomal region); acrosome status (non-viable cells and acrosome-reacted cells; via 7-AAD and FITC; flow cytometry); sperm-zona pellucida binding (binding capacity; hemizona assay)
investigated material: spermatozoa
time of investigation: after exposure
Main outcome of study (according to author)
The irradiation did not affect the acrosome reaction. The analysis of morphometric parameters revealed a statistically significant reduction in all the morphometric parameters of exposed sperm samples compared with unexposed controls. There was a statistically significant reduction in zona pellucida binding in exposed sperms compared with that in controls.
The authors conclude that although radiofrequency electromagnetic field exposure did not adversely affect the acrosome reaction, it had a significant effect on sperm morphometry. In addition, a significant decrease in sperm binding to the hemizona was observed. These results could indicate a significant effect of radiofrequency electromagnetic field on sperm fertilization potential.
(Study character: medical/biological study, experimental study, full/main study)
Study funded by
- National Research Foundation (NRF), Pretoria, South Africa
- South African Bureau of Standards (SABS)
Published comments on this article:
- Avendano C et al. (2012): Use of laptop computers connected to internet through Wi-Fi decreases human...
- Celik S et al. (2012): An evaluation of the effects of long-term cell phone use on the testes via...
- Gutschi T et al. (2011): Impact of cell phone use on men's semen parameters.
- Otitoloju AA et al. (2010): Preliminary study on the induction of sperm head abnormalities in mice, Mus...
- Falzone N et al. (2010): Mobile Phone Radiation Does Not Induce Pro-apoptosis Effects in Human...
- Kesari KK et al. (2010): Microwave exposure affecting reproductive system in male rats.
- Salama N et al. (2010): Effects of exposure to a mobile phone on testicular function and structure in...
- Agarwal A et al. (2009): Effects of radiofrequency electromagnetic waves (RF-EMW) from cellular phones...
- De Iuliis GN et al. (2009): Mobile phone radiation induces reactive oxygen species production and DNA...
- Falzone N et al. (2008): In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane...
- Agarwal A et al. (2008): Effect of cell phone usage on semen analysis in men attending infertility...
- Dasdag S et al. (2008): Mobile phone exposure does not induce apoptosis on spermatogenesis in rats.
- Wdowiak A et al. (2007): Evaluation of the effect of using mobile phones on male fertility.
- Iorio R et al. (2007): A preliminary study of oscillating electromagnetic field effects on human...
- Deepinder F et al. (2007): Outlook - Cell phones and male infertility: dissecting the relationship.
- Erogul O et al. (2006): Effects of electromagnetic radiation from a cellular phone on human sperm...
- Fejes I et al. (2005): Is there a relationship between cell phone use and semen quality?
- Ozguner M et al. (2005): Biological and morphological effects on the reproductive organ of rats after...
- Davoudi M et al. (2002): Der Einfluß elektromagnetischer Wellen auf die Spermienmotilität
- Dasdag S et al. (1999): Whole-body microwave exposure emitted by cellular phones and testicular...
, electromagnetic field
, flow cytometry
, full/main study
, mobile communication
, mobile phone
, zona pellucidaExposure: mobile communication
system, digital mobile phone
Do you want to give a feedback on our extract of the article?