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Medical/biological Study (experimental study)Possible Combined Effects of 900 MHz Continuous-Wave Electromagnetic Fields and Gentamicin on the Auditory System of Rats. med./biol. By: Parazzini M, Galloni P, Piscitelli M, Pinto R, Lovisolo GA, Tognola G, Ravazzani P, Marino C Published in: Radiat Res 2007; 167 (5): 600 - 605 ( PubMed Entry , Journal web site )Aim of study (according to author) To evaluate the cochlear functionality of rats exposed to electromagnetic fields at 900 MHz and to gentamicin (loss of hearing or balance is a well-documented adverse effect of such aminoglycoside antibiotics). Background/further details: 32 rats were divided into four groups: group 1 was treated with daily intramuscular injections of gentamicin for 15 days (150 mg/kg); group 2 was treated with daily intramuscular injections of gentamicin for 15 days (same dose) and exposed to electromagnetic fields; group 3 was exposed to electromagnetic fields; group 4 was sham-exposed. Endpoint Exposure General category: mobile communication system, mobile phone, GSM, microwaves | Field characteristics | Parameters |
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900 MHz  continuous wave (CW) exposure duration: repeated daily exposure, 2 h/day, 5 days/week, for 4 weeks
| SAR: 4 W/kg
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FIELD View further expo parametersExposed system: animal (species/strain): rat/Sprague-Dawley partial body exposure: head/ear Methods Endpoint/Measurement parameters/Methodology investigation on living organism investigated organ system: sense organs, ear
time of investigation: before, during and after exposure
Main outcome of study (according to author) The data showed no evidence of a combined effect of a radiofrequency electromagnetic field exposure and gentamicin on the auditory system of rats under these experimental conditions. (Study character: medical/biological study, experimental study, full/main study, blind study)
Study funded by - European Project GUARD ("Potential adverse effects of GSM cellular phones on hearing")
- European Union (EU)/European Commission
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Glossary: aminoglycoside antibiotics, animal, auditory, biological, blind study, cochlear, CW, distortion product otoacoustic emissions, dose, ear, electromagnetic field, endpoint, evidence, exposed, exposure, full/main study, Gentamicin, GSM, injections, MHz, microwaves, mobile communication, mobile phone, organism, partial body exposure, radiofrequency, rat/Sprague-Dawley, rats, SAR, sense organs, sham-exposed, species, strain |
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