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Medical/biological Study (experimental study)Syrian hamster dermal cell immortalization is not enhanced by power line frequency electromagnetic field exposure. med./biol. By: Gamble SC, Wolff H, Arrand JE
Published in: Br J Cancer 1999; 81 (3): 377 - 380 (  PubMed Entry , Journal web site )Aim of study (according to author)
This in vitro study was performed to investigate the effects of electromagnetic fieds on the cell immortalization of hamster dermal cells in the presence or absence of a known carcinogen (gamma radiation, at 0.5 or 1.5 Gy)
Background/further details:
Syrian hamster dermal cells were chosen as investigated cell line as they show very low frequency of spontaneous immortalization. Cell immortalization can be a sign of tumor initiation.
The cells were exposed to electromagnetic fields at the levels commonly encountered in the home. Endpoint Exposure
General category: magnetic field, 50/60 Hz (AC), power transmission line
FIELD View further expo parametersExposed system:
intact cell/cell culture (in vitro)
SHD (syrian hamster dermal) cells Methods
Endpoint/Measurement parameters/Methodology investigated material: intact cell/cell culture (in vitro)
time of investigation: after exposure
Main outcome of study (according to author)
The electromagnetic field exposure alone did not cause cell immortalization in the investigated cell line. Furthermore the electromagnetic fields exposures did not enhance the frequency of ionizing radiation-induced immortalization. (Study character: medical/biological study, experimental study, full/main study, blind study, randomized)
Study funded by - EMF Biological Research Trust (EMFBRT), UK
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Glossary: 50/60 Hz, AC, biological, blind study, carcinogen, cell, cell culture, cell division, cell line, cell viability, colonies, CW, DC, dermal, electromagnetic, electromagnetic field, endpoint, exposed, exposure, frequency, full/main study, gamma radiation, Gy, immortalized, induced, in vitro, ionizing radiation, low frequency, magnetic field, magnetic flux density, power transmission line, proliferation, randomized, tumor initiation |
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