Medizinisch/biologische Studie (experimentelle Studie/Beobachtungsstudie)

Cytogenetic investigation of subjects professionally exposed to radiofrequency radiation. med./biol.

PubMed Eintrag

Journal Website

Ziel der Studie (lt. Autor)
Es sollten die zytogenetischen Wirkungen in peripheren Blut-Lymphozyten von 49 Personen untersucht werden, die berufsbedingt bei elektromagnetischen Mobilfunk-Feldern exponiert waren (Funk-Ingenieure und andere Personen, die für zwei der Belgischen Mobilfunk-Betreiber arbeiteten).
Hintergrund/weitere Details:
Die Blutzellen der Testpersonen wurden ebenfalls bei dem Mutagen Mitomycin C exponiert, um mögliche kombinierte Wirkungen einer Hochfrequenz-Befeldung und der Chemikalie zu untersuchen.
Die Ergebnisse wurden mit denen von 25 nicht-exponierten Kontrollpersonen verglichen.

Endpunkt

• Genotoxizität/Mutation: DNA-Schaden (Komet-Assay, Schwesterchromatid-Austausch und Chromosomenaberrationen)

Exposition/Befeldung
Allgemeine Kategorie: Mobilfunk-Basisstation, berufliche Exposition

Feldeigenschaften	Parameter
Feld 1: 450 - 900 MHz Expositionsdauer: täglich wiederholte Exposition, mindestens 1 h/Tag für 2,3 Jahre (im Durchschnitt)
Feld 2: 147,25 MHz - 40 GHz Expositionsdauer: täglich wiederholte Exposition während der Arbeit

Exponiertes System:
Mensch
Ganzkörperexposition
Blut-Proben

Methoden
Endpunkt/Messparameter/Methodik

• Genotoxizität/Mutation: DNA-Schaden (alkalischer Komet-Assay, Schwesterchromatid-Austausch (Giemsa-Färbung) und Chromosomenaberrationen (Fluoreszenz-plus-Giemsa-Färbung))

Hauptergebnis der Studie (lt. Autor)
Der Komet-Assay, die Tests für den Schwesterchromatid-Austausch und die Chromosomenaberrationen lieferten keinen Nachweis für Hochfrequenz-induzierte genotoxische Wirkungen.
Es wurde ebenfalls, weder unter Verwendung des Komet-Assays noch im Schwesterchromatid-Austausch-Test, keine gemeinsame Wirkung von der elektromagnetischen Feld-Exposition der Blutzellen und dem Mutagen gefunden

(Studienmerkmale: medizinisch/biologische Studie, experimentelle Studie, Beobachtungsstudie, Voll-/Hauptstudie)

Studie gefördert durch

• nicht angegeben/keine Förderung

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