Effects of long-term 50 Hz magnetic field exposure on the micro nucleated polychromatic erythrocyte and blood lymphocyte frequency and argyrophilic nucleolar organizer regions in lymphocytes of mice med./bio.

[Wirkungen einer anhaltenden 50 Hz-Magnetfeld-Exposition auf die Häufigkeit mikronukleärer polychromatischer Erythrozyten und Blut-Lymphozyten und die argyrophilen Nukleolus-organisierenden Regionen in den Lymphozyten von Mäusen]

Ziel der Studie (lt. Autor)

Hintergrund/weitere Details

Endpunkt

• Genotoxizität/Mutation: Mikronukleus-Bildung in den Blutzellen
• Blutzellen-Eigenschaften

Exposition/Befeldung (teilweise nur auf Englisch)

• • 50/60 Hz
  • magnetisches Feld
  • Niederfrequenz

Vollständige Ansicht Kompaktansicht

Methoden Endpunkt/Messparameter/Methodik

• Genotoxizität/Mutation: Mikronukleus-Bildung in den Erythrozyten (Anzahl der mikronukleären polychromatischen Erythrozyten und Lymphozyten; modifizierte Giemsa-Färbung, Lichtmikroskopie)
• Blutzellen-Eigenschaften (Zell-Nukleus-Fläche und Silber-Färbung der Nukleolus-Organizer-Region (Fläche und AgNOR-Anzahl pro Nukleus; als Marker für die Nukleolus-Aktivität und Transkription))
• Körpergewicht, Futter- und Wasser-Verbrauch

Hauptergebnis der Studie (lt. Autor)

Studie gefördert durch

• Selcuk University, Turkey

Themenverwandte Artikel

• Udroiu I et al. (2015): Genotoxicity induced by foetal and infant exposure to magnetic fields and modulation of ionising radiation effects
• Alcaraz M et al. (2014): Effect of long-term 50 Hz magnetic field exposure on the micronucleated polychromatic erythrocytes of mice
• Miyakoshi Y et al. (2012): Tempol suppresses micronuclei formation in astrocytes of newborn rats exposed to 50-Hz, 10-mT electromagnetic fields under bleomycin administration
• Udroiu I et al. (2010): Genotoxic properties of extremely low frequency electromagnetic fields
• Cakir DU et al. (2009): Alterations of Hematological Variations in Rats Exposed to Extremely Low Frequency Magnetic Fields (50Hz)
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• McNamee JP et al. (2005): Evaluating DNA damage in rodent brain after acute 60 Hz magnetic-field exposure
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• Abramsson-Zetterberg L et al. (2001): Extended exposure of adult and fetal mice to 50 Hz magnetic field does not increase the incidence of micronuclei in erythrocytes
• Svedenstal BM et al. (1999): DNA damage, cell kinetics and ODC activities studied in CBA mice exposed to electromagnetic fields generated by transmission lines
• Svedenstal BM et al. (1999): DNA damage induced in brain cells of CBA mice exposed to magnetic fields
• Svedenstal BM et al. (1998): Leukocytes and micronucleated erythrocytes in peripheral blood from mice exposed to 50 Hz or 20 kHz magnetic fields
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